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Intrathecal delivery of recombinant AAV1 encoding hepatocyte growth factor improves motor functions and protects neuromuscular system in the nerve crush and SOD1-G93A transgenic mouse models

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840 Consistent with this, switch III mutants effectively uncouple GTP hydrolysis from cofactor transfer from ATR, in that significant cofactor transfer occurs in the presence of a nonhydrolyzable GTP analog, GMPPNP

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(2.2 lb = 1 kg) 5